A paper was recently published by researchers at McMaster University in Canada, describing how cannabigerol potentially killed various strains of MRSA – the antibiotic-resistant staph bacteria. The team of researchers led by Eric D. Brown had taken a step further from the petri dish and started testing CBD on rodents. Their results could potentially be the first step in an attempt to make CBG the newest antibiotic in the market.
MRSA in hospitals
MRSA is an infection of the skin and soft tissues, which causes red pus-filled bumps and sores. While MRSA is not an infamous problem in hospitals worldwide, staph bacteria ( Staphylococcus aureus) is carried by one in three people in their nose. Although a common bacteria, unless it enters an open wound – which could lead to a sometimes deadly infection, it is generally harmless.
Antibiotics can successfully treat most staph infections, but antibiotic-resistant staph, known as MRSA, has proven to be dangerous. MRSA can be carried by 5 in 100 people. Although they are generally mild infections, difficulty in treatment has been shown. MRSA could potentially prove to be fatal for people with suppressed immune systems in hospitals.
Cannabis – An antibacterial agent
Cannabis has been known for its antibacterial properties. While early researchers had some ambiguity regarding the active specific compounds, recent research has been able to recognize which cannabinoids are effective against which bacteria.
When 18 cannabinoids were tested against common strains of MRSA by the McMaster University team, almost all of them had shown some efficacy against the bacteria. Most effectiveness was shown by seven cannabinoids including CBG, CBD, CBN, CBCA, Δ9-THC, and Δ8-THC. They were able to kill the bacteria at concentrations that were low enough to warrant further investigation. Moreover, CBG showed efficacy at specifically low concentrations.
CBG to kill MRSA
The biofilm that bacterial cells develop for protection makes MRSA difficult to treat. However, it appears that CBG is able to strip away MRSA’s biofilm, also leaving our blood cells’ defenses intact.
CBG helps prevent the formation of the biofilm, while also being able to strip it away. That is probably the reason that even low concentrations of CBG are effective at killing MRSA.
The question, however, is, whether CBG would do the same to blood cells. Such reactions would be a major signal to halt further research. However, researchers have reported healthy human red blood cells even after the exposure to CBG.
Treatment of MRSA in Humans
Conventionally in drug evolution, a compound is tested on animals, only after it has shown efficacy in a petri dish. The McMaster researchers treated mice with CBG and concluded that it reduced the animals’ bacterial load by half.
100mg/kg of injected CBG was proven to be the most effective dose to kill bacteria. Scaling it to human size, it would be a hefty dose. It would roughly be a quarter-ounce of puer CBG for a 154-pound human. Additionally, the general medical applications of cannabinoids have been oral, oromucosal, or intranasal, and not injected.
The Balance of Efficacy and Safety
According to researcher Eric D. Brown, despite the generally high doses of antibiotics compared to other medications, the need for safety and tolerability has to be taken under consideration when talking about the need for high doses of antibiotics to achieve efficacy. He further added how this is one of the reasons for failure in antibiotic drug discovery and development. He believes the balance between efficacy and tolerability is hard to achieve and which is why MRSA remains a problem. However, it may not be too far-fetched to envision a day when we can use CBG for the treatment of MRSA.
Cannabidiol Oil – A Trending Lifestyle
The use of Cannabidiol oil in the daily routine is becoming popular by the day. This oil comes with many benefits. In addition to other healthy activities dedicated to physical strength and apparent beauty, people are considering the use of Cannabidiol oil mixed with some other essential oils in their daily healthcare routine.
The importance of Cannabis Sativa is manifold. The strain is in very common use. People nowadays are much more health-conscious. They care about every single detail in their daily routine.
With increasing population, pollution is also becoming greater. With increased pollution, maintenance of body issues is also becoming more and more complex.
You can find detailed and cautious routines in every corner. There are many myths and facts about CBD oil. Now things are different. The various facts about this oil got uncovered after recent researches.
Federal authorities are also trying their best to maintain quality standards. FDA is putting effort into grading different strengths and lags of Cannabis products.
Cannabis sativa was previously indigenous to Asia only. However, it is now cultivated on large scales worldwide. The strain goes back until the recorded history. It is known for use in seed oil, industrial fibre, food, recreation and spiritual moods.
However, this practice can also prove adverse in certain circumstances. People might try to use this as an opportunity to misuse cannabis products.
Physicians address public with concern in this regard. They promote the controlled use of marijuana and other cannabis products. Excess of anything is bad so people should observe a calculated use.
There are many celebrities worldwide who have added CBD oil to their daily routine. CBD stands for Cannabidiol. In cannabis plant called cannabis Sativa, a chemical bond forms called cannabinoid.
The cannabinoid is a type of CBD or THC. It has a high psychoactive effect and is main to be used for relaxation. In most of the markets, Cannabidiol oil is sold with THC for marketing purposes.
CBD oil has many benefits of which we will discuss some in the following paragraphs:
Gymnasts and athletes face a lot of muscle problems. Whenever a muscle in any part of body becomes sore, you can’t do anything properly.
Cannabidiol oil is very beneficial for such problems. You can deal with muscle soreness by applying this oil mixed with other oils.
This oil offers comfort and reduces pain in a very smooth way. This is also the reason why patients having arthritis find relief in this drug.
The properties of cannabidiol oil make it a perfect candidate as a depression reliever. The sense of euphoria can make you fly away from worldly troubles for some time.
This medical use of marijuana is without a doubt very important. It is also helpful in other neurological conditions such as anxiety, sleep deprivation etc.
Cannabidiol oil is very beneficial, and these perks are due to healthy constituents. It has vitamin B, C and E which help in the healthy development of the human body.
Other useful components of this oil include phosphorus, zinc, magnesium and many more. With the help of these components, you can remain healthy and happy with lesser worries.
A healthy lifestyle means you can focus on being productive. You are no longer worried about back pain and those wrinkles. You should make a decision fast and add Cannabidiol oil and other healthy ingredients in your daily routine.
Cannabis Shown To Be Effective In Treating Depression and Anxiety
There’s nothing like a good night’s sleep to relax the body and mind. We’ve all heard that saying, and most of us take the hours of sleep we get for granted. If we feel tired after work, we don’t really mind, because we can easily fall asleep a bit earlier, right? But imagine if you couldn’t sleep. Or if you felt so anxious at night that falling asleep terrifies you. These are real problems facing a huge number of people today, especially those with clinical depression.
Mental health disorders are responsible for worsening physical health disorders and reducing quality of life. The two most commonly faced forms are depressive disorders and anxiety disorders. Understandably, a worldwide pandemic leaving billions detached from their friends and family has made things worse. In times as uncertain as ours, there’s plenty to be depressed or anxious about too. Luckily, studies have shown that cannabis can be a powerful combatant against these two conditions, as we’ll see below.
What’s the difference between being depressed and depression?
While it is basically a normal to undergo ups and downs in life that affect your mindset, we’re not talking about just feeling sad or worried. Almost everyone experiences moments where things seem pointless or bleak. That’s part of life and while it isn’t good, it isn’t a disorder. Disorders are defined as a period of depression lasting consistently over more than six month.
Depressive disorders, commonly called depression, are among the most common ailments affecting people today. And what’s worse is that they are either caused by or cause anxiety disorders as well. Again, that’s not like anxiety from not submitting homework on time. Anxiety disorders can cause breathing problems so bad, they are sometimes confused with heart attacks.
Okay, so how common is it?
You’ve probably heard a lot about ‘mental health awareness week’ or maybe charity events for people with mental health problems, but no matter how much they talk about it on the news, it’s still not enough. Because it’s suspected that as many as one in five people worldwide are suffering from serious mental health issues right now. And at some point in life, most people experience those issues too. It’s a pandemic like COVID-19, but we don’t even know how bad it is.
Of all the people who experience these issues, only thirty six percent even get checked out. That means we don’t even know how common it is for people to be suffering from mental health problems. The situation, extremely dire as it is, needs more awareness and discussion.
Luckily, an age old remedy is making news
Since time immemorial, people have been smoking select plants for their psychoactive effects. Even monkeys like using cannabis, and it might be for a lot of the reasons we do too. Besides the pleasurable effects of the drug, in particular certain benefits need to be less overlooked: marijuana fights depressive and anxiety disorders. This is due to the THC (tetrahydrocannabinol) and CBD (cannabidiol) that play psychoactive and physiological roles respectively.
Marijuana, linked, fortunately, to lowering negative thought processes in patients, saves lives. Also, it typically grants very soothing, relaxing sleep for those with insomnia issues. People who find difficulty in relaxing before bed have commonly used the drug to help rest more comfortably. And this isn’t news to us; indigenous peoples have been using cannabis for centuries. We owe a lot to these cultures, after all.
How Cannabis Is Now Being Used To Treat COVID-19
The novel coronavirus has taken hold of our lives and many live in fear of getting sick. In times where nothing is certain, there is a ray of hope beaming through the gloom. And it comes wrapped in paper for your convenience. It is cannabis, and it may just save lives.
Researchers have good evidence that leads them to believe there’s more to weed than meets the eye. In some tests, they were able to show with confidence that cannabis contains chemicals that reduce inflammation from COVID-19. We discuss the news and its highlights below.
The chemical in question is Cannabidiol Oil, or CBD Oil, as it is commonly known. Scientists at the Dental College of Georgia and the Medical Dental College of Georgia have made significant strides in proving this chemical is helpful in fighting the virus.
What is inflammation and why is it bad?
Inflammation is a medical term for one of the responses shown by the body to infection. Cutting the jargon out, this means when your body gets infected by a bacterium or virus, it can choose how to react. One of the ways cells that are right at the site of infection respond is by releasing special messenger chemicals which alert the body to the invading pathogen. This is the equivalent of raising the alarm for intruders. One bad side effect of this, though, is that sometimes, it can hurt you worse than the intruders. Inflammation causes reddening of the skin, swelling, heat and other bothersome effects.
Along with inflammation, the body has many other ways to respond to pathogens (disease causing particles). However, in the context of coronavirus and its side effects, these are not important so we will not discuss them.
What does CBD Oil do, and how does it help against coronavirus?
Cannabidiol is a compound found in most species of cannabis. Such compounds that are present in cannabis plants are usually referred to as cannabinoids. CBD Oil is unusual even among cannabinoids because it helps fight against the inflammation response of the body.
To avoid boring you with all the details suffice it to say that when you get a fever, that isn’t because of the pathogen inside you. A fever is caused by the body itself because it raises the temperature of the blood. This can kill pathogens, but it can also kill you if it goes on for too long. One way CBD Oil can help is by putting a stop on all that. It causes chemical reactions to take place that don’t allow the body to respond so drastically to the virus. Instead, the Oil moderates a better response that doesn’t hurt you as much.
What does this mean for the future of cannabis?
For now, it’s really good news. It means that cannabis has a shot at making it big in the medical industry. If medical industries push for cannabis legalization to help keep up with demand, it’s a win for everyone. Also, using cannabis in medicine hasn’t been a practice for centuries, but this new research is definitely promising.
If the research holds up on a much larger scale, it could turn the rides for those demanding better cannabis laws. For starters, if the drug can be used to treat COVID-19 patients, then it’s great for the majority of the world. Also, it will help to normalize marijuana and show that this drug isn’t what it’s made out to be. Lastly, it will help create more demand and that means better regulation for cannabis overall.
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